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Preliminary results published in 2003 from the Women’s Health Initiative clinical trial linked a combination of estrogen and progestin with an increased risk of heart disease, stroke, blood ...
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Estrogen can also reduce vaginal atrophy and increase sexual arousal, frequency and orgasm. [21] The effectiveness of hormone replacement can decline in some women after long-term use. [21] A number of studies have also found that the combined effects of estrogen/androgen replacement therapy can increase libido and arousal over estrogen alone. [21]
Estrogens may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. [65] [66] It is also commonly used during in vitro fertilization (IVF). Estrogen helps maintain the endometrial lining of the uterus and help prepare for pregnancy.
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis.