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  2. Diabetes and deafness - Wikipedia

    en.wikipedia.org/wiki/Diabetes_and_deafness

    Diabetes and deafness (DAD) or maternally inherited diabetes and deafness (MIDD) or mitochondrial diabetes is a subtype of diabetes which is caused from a mutation in mitochondrial DNA, which consists of a circular genome. It is associated with the genes MT-TL1, MT-TE, and MT-TK. [1]

  3. Carlson curve - Wikipedia

    en.wikipedia.org/wiki/Carlson_Curve

    The term was coined by The Economist [3] and is named after author Rob Carlson. [1]Carlson curves illustrate the rapid (in some cases above exponential growth) decreases in cost, and increases in performance, of a variety of technologies, including DNA sequencing, DNA synthesis and a range of physical and computational tools used in protein production and in determining protein structures.

  4. Genetic causes of type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Genetic_causes_of_type_2...

    Decreasing the level these gene products reduce the body's ability to handle glucose, which leads to the increased risk of diabetes. Since 2019 large sequencing studies have started to identify rare coding variants associated with type 2 diabetes risk, including variants in PAM and SLC30A8. [16]

  5. Personal genomics - Wikipedia

    en.wikipedia.org/wiki/Personal_genomics

    The cost of sequencing a human genome is dropping rapidly, due to the continual development of new, faster, cheaper DNA sequencing technologies such as "next-generation DNA sequencing". The National Human Genome Research Institute, an arm of the U.S. National Institutes of Health , has reported that the cost to sequence a whole human-sized ...

  6. 1000 Genomes Project - Wikipedia

    en.wikipedia.org/wiki/1000_Genomes_Project

    The third pilot study involves sequencing the coding regions of 1,000 genes in 1,000 people with deep coverage (20×). [14] [15] It was estimated that the project would likely cost more than $500 million if standard DNA sequencing technologies were used.

  7. Clinical metagenomic sequencing - Wikipedia

    en.wikipedia.org/.../Clinical_metagenomic_sequencing

    The untargeted analysis is a metagenomic Shotgun sequencing approach. The whole DNA and/or RNA is sequenced with this approach using universal primers. The resultant mNGS reads can be assembled into partial or complete genomes. These genome sequences allow to monitor hospital outbreaks to facilitate infection control and public health surveillance.