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Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
In patients with sepsis, septic shock, or multiple organ dysfunction syndrome that is due to major trauma, the rs1800625 polymorphism is a functional single nucleotide polymorphism, a part of the receptor for advanced glycation end products (RAGE) transmembrane receptor gene (of the immunoglobulin superfamily) and confers host susceptibility to ...
Those with severe ischemia who develop complications such as sepsis, intestinal gangrene, or bowel perforation may require more aggressive interventions such as surgery and intensive care. Most patients make a full recovery; occasionally, after severe ischemia, patients may develop long-term complications such as a stricture [7] or chronic ...
Overwhelming post-splenectomy sepsis (OPSS) [1] Specialty: Infectious disease: Usual onset: 24–48 hours following presentation with mild viral symptoms [2] Causes: Exposure to pathogens following splenectomy or asplenia: Risk factors: Splenectomy in the past 2–3 years, removal of spleen for hematological reasons, being under the age of 2 [2 ...
The Sepsis Six is the name given to a bundle of medical therapies designed to reduce mortality in patients with sepsis. [citation needed] Drawn from international guidelines that emerged from the Surviving Sepsis Campaign [1] [2] the Sepsis Six was developed by The UK Sepsis Trust. [3] (Daniels, Nutbeam, Laver) in 2006 as a practical tool to ...
A common cause of sepsis is bacterial pneumonia, frequently the result of infection with streptococcus pneumoniae. Patients with sepsis require intensive care with blood pressure monitoring and support against hypotension. Sepsis can cause liver, kidney and heart damage. Respiratory failure - CAP patients often have dyspnea, which may require ...
Bacteremia can have several important health consequences. Immune responses to the bacteria can cause sepsis and septic shock, which, particularly if severe sepsis and then septic shock occurs, have high mortality rates, especially if not treated quickly (though, if treated early, currently mild sepsis can usually be dealt with successfully). [6]
Patients may develop sepsis, a life-threatening response to infection, which may appear as an increased heart rate, increased breathing rate, fever, and confusion. [2] This may progress to multi-level organ dysfunction, including acute respiratory and kidney failure.