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  2. Maalox - Wikipedia

    en.wikipedia.org/wiki/Maalox

    The antacid, Maalox Maalox was a brand of antacid owned by Sanofi.Their main product is a flavored liquid containing a suspension of aluminum hydroxide and magnesium hydroxide, which act to neutralize or reduce stomach acid, for the purpose of relieving the symptoms of indigestion, heartburn, gastroesophageal reflux disease, and also stomach or duodenal ulcers.

  3. Methylmalonic acidemias - Wikipedia

    en.wikipedia.org/wiki/Methylmalonic_acidemias

    Treatment for all forms of this condition primarily relies on a low-protein diet, and depending on what variant of the disorder the individual suffers from, various dietary supplements. All variants respond to the levo isomer of carnitine as the improper breakdown of the affected substances results in sufferers developing a carnitine deficiency.

  4. Methylmalonyl-CoA mutase deficiency - Wikipedia

    en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase...

    Although methylmalonic acidemia has a variety of causes, both genetic and dietary, methylmalonyl CoA mutase deficiency is an autosomal recessive genetic disorder. Patients with the deficiency either have a complete gene lesion, designated as mut0 or a partial mutation in the form of a frameshift designated as mut-.

  5. William H. Rorer, Inc. - Wikipedia

    en.wikipedia.org/wiki/William_H._Rorer,_Inc.

    Maalox was developed in collaboration between William H. Rorer, Inc. and a medical doctor and researcher specializing in gastrointestinal issues, Alison Howe Price from Philadelphia. [3] The collaboration came about after World War II when Claude Newhart, a salesman and pharmacist for the company had an idea that he thought might change the ...

  6. Malonic aciduria - Wikipedia

    en.wikipedia.org/wiki/Malonic_aciduria

    Malonic aciduria or malonyl-CoA decarboxylase deficiency (MCD) is an autosomal-recessive [1] metabolic disorder caused by a genetic mutation that disrupts the activity of Malonyl-CoA decarboxylase. This enzyme breaks down Malonyl-CoA (a fatty acid precursor and a fatty acid oxidation blocker) into acetyl-CoA and carbon dioxide .

  7. Organic acidemia - Wikipedia

    en.wikipedia.org/wiki/Organic_acidemia

    Most of the organic acidemias result from defective autosomal genes for various enzymes important to amino acid metabolism.Neurological and physiological harm is caused by this impaired ability to synthesize a key enzyme required to break down a specific amino acid, or group of amino acids, resulting in acidemia and toxicity to specific organs systems.

  8. Olipudase alfa - Wikipedia

    en.wikipedia.org/wiki/Olipudase_alfa

    Olipudase alfa was approved for medical use in Japan in March 2022. [6]In May 2022, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Xenpozyme, intended for the treatment of non-central nervous system (CNS) manifestations of acid ...

  9. NGLY1 deficiency - Wikipedia

    en.wikipedia.org/wiki/NGLY1_deficiency

    NGLY1 deficiency is a very rare genetic disorder caused by biallelic pathogenic variants in NGLY1. It is an autosomal recessive disorder. Errors in deglycosylation are responsible for the symptoms of this condition. [ 1 ]