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[2] [4] As depression is also associated with pro-inflammatory responses, the suggestion is that the causes of depression are little different from the causes of the autoimmune diseases it is largely co-morbid with, with sanitary environments increasing the risk of excessive inflammation in response to psychosocial stressors just as it is ...
Treatments can address underlying feelings and emotional conflicts that can lead to psychogenic pain, as well as other potential causes of dysfunction with behavior, affect, and coping that can be seen in patients. [10] In cases where therapy and medication do not show results, some may consider surgical intervention.
Several theories concerning the biologically based cause of depression have been suggested over the years, including theories revolving around monoamine neurotransmitters, neuroplasticity, neurogenesis, inflammation and the circadian rhythm. Physical illnesses, including hypothyroidism and mitochondrial disease, can also trigger depressive ...
However inflammation can also have negative effects. [3] Too much inflammation, in the form of chronic inflammation, is associated with various diseases, such as hay fever, periodontal disease, atherosclerosis, and osteoarthritis. Inflammation can be classified as acute or chronic.
Similarly, one of the main causes of persistent musculoskeletal pain is ongoing inflammation. Inflammation-related pain symptoms include heightened sensitivity to stimuli in the afflicted area. In rheumatological disorders with inflammation as the principal pathophysiological mechanism, chronic secondary musculoskeletal pain can be the main ...
It’s an inflammatory disease with no cure that can cause the bones in the spine to fuse over time, according to the Mayo Clinic. Symptoms typically begin in early adulthood, with back pain ...
The mood effects caused by interleukin-6 following an immune response have been linked to increased activity within the subgenual anterior cingulate cortex, [32] an area involved in the etiology of depression. [33] Inflammation-associated mood change can also produce a reduction in the functional connectivity of this part of the brain to the ...
Sadness is a common experience in childhood. Sometimes, sadness can lead to depression. Some families may have a (conscious or unconscious) rule that sadness is "not allowed", [3] but Robin Skynner has suggested that this may cause problems, arguing that with sadness "screened off", people can become shallow and manic.