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[4] [5] Today Diffuse lipoblastoma is the preferred term for lipoblastomatosis. [6] [7] The tumor is rare, accounting for less than 1% of all childhood neoplasm, [8] and it has been found to be more common in males than females. [9] [8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the ...
Lipoblasts (white arrow) and lipocytes (black arrow), in a case of lipoblastoma. Micrograph showing a lipoblast (left-bottom of image) in a liposarcoma. H&E stain.
Lipoblastoma is a type of rare, subcutaneous, benign, fatty tumor, [1] [2] found in infants, and children, more common in males with tendency of local recurrence. Local recurrence can happen in up to 80% of incompletely resected tumours.
Mesenchymal invasion has been detected during the development of melanoma, fibrosarcoma, glioblastoma, and other malignancies. [2] Most of the cancer cells that detach from the tumor mass and invade the surrounding tissues are known to undergo certain changes, acquiring the morphological properties and a phenotype typical of mesenchymal cells.
This is a mechanism through which cancer cells lose their epithelial properties resulting in a loss of cell-cell adhesion and a transition towards mesenchymal-like properties . EMT plays a diverse and essential role in adhesion, motility and morphology of cells under both normal and pathological conditions.
A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues.
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