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The exact prevalence of obesity hypoventilation syndrome is unknown, and it is thought that many people with symptoms of OHS have not been diagnosed. [4] About a third of all people with morbid obesity (a body mass index exceeding 40 kg/m 2) have elevated carbon dioxide levels in the blood. [5]
Rapid-onset obesity with hypothalamic dysregulation, hypoventilation, and autonomic dysregulation (ROHHAD) is a rare condition whose etiology is currently unknown. [1] ROHHAD mainly affects the endocrine system and autonomic nervous system, but patients can exhibit a variety of signs.
[6] Central hypoventilation syndrome is caused by certain receptors in the brain failing to recognize changes in carbon dioxide levels during sleep, leading to a low breathing rate and low blood concentration of oxygen. Some of the causes of this disease are sudden onset obesity or spinal cord surgery.
Hypercapnia is generally caused by hypoventilation, lung disease, or diminished consciousness. It may also be caused by exposure to environments containing abnormally high concentrations of carbon dioxide, such as from volcanic or geothermal activity, or by rebreathing exhaled carbon dioxide .
Based on their findings, the researchers recommend that people with obstructive sleep apnea or obesity hypoventilation syndrome, which is a breathing disorder, avoid alcohol for 12 hours prior to ...
People with obesity hypoventilation syndrome often require NIV initially in their care, but many can be switched to CPAP. [2] American Thoracic Society (ATS) clinical practice guidelines recommend that NIV is provided on discharge with a further sleep study assessment as an outpatient. [11]
The term "Pickwickian syndrome" that is sometimes used for the syndrome was coined by the famous early 20th-century physician William Osler, who must have been a reader of Charles Dickens. The description of Joe, "the fat boy" in Dickens's novel The Pickwick Papers, is an accurate clinical picture of an adult with obstructive sleep apnea syndrome.
dramatic increase in obesity. In 1991, only four states had obesity prevalence rates as high as 15-19% and not a single state had a rate above 20%. By 2005, only four states reported rates below 20%, with 17 states registering rates equal to or above 25% (Center for Disease Control and Prevention, 2006).