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  2. Response evaluation criteria in solid tumors - Wikipedia

    en.wikipedia.org/wiki/Response_Evaluation...

    This distinction must be made by both the treating physicians and the cancer patients themselves. Many oncologists in their daily clinical practice follow their patients' malignant disease by means of repeated imaging studies and make decisions about continuing therapy on the basis of both objective and symptomatic criteria.

  3. Clinical Cancer Research - Wikipedia

    en.wikipedia.org/wiki/Clinical_Cancer_Research

    Clinical Cancer Research is a peer-reviewed medical journal on oncology, including the cellular and molecular characterization, prevention, diagnosis, and therapy of human cancer, medical and hematological oncology, radiation therapy, pediatric oncology, pathology, surgical oncology, and clinical genetics.

  4. Immune-related response criteria - Wikipedia

    en.wikipedia.org/wiki/Immune-Related_Response...

    The initial evidence cited by the creators of the irRC that their criteria were useful lay in the two Phase II melanoma trials described in the Clinical Cancer Research paper. The drug being trialled was a monoclonal antibody called ipilimumab, then under development at BMS with Axel Hoos as the medical lead.

  5. Cancer research - Wikipedia

    en.wikipedia.org/wiki/Cancer_research

    Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments.

  6. Clinical endpoint - Wikipedia

    en.wikipedia.org/wiki/Clinical_endpoint

    Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ...

  7. MammaPrint - Wikipedia

    en.wikipedia.org/wiki/MammaPrint

    MammaPrint can change clinical practice by providing critical prognostic information to aid in assessing patients’ risk for distant metastasis and potentially sparing over one hundred thousand women annually with early-stage breast cancer worldwide from unnecessary toxicities and side effects from chemotherapy and creating considerable cost ...

  8. Cancer of unknown primary origin - Wikipedia

    en.wikipedia.org/wiki/Cancer_of_unknown_primary...

    Cancer of unknown primary origin (CUP) is a cancer that is determined to be at the metastatic stage at the time of diagnosis, but a primary tumor cannot be identified. A diagnosis of CUP requires a clinical picture consistent with metastatic disease and one or more biopsy results inconsistent with a tumor cancer.

  9. Loncastuximab tesirine - Wikipedia

    en.wikipedia.org/wiki/Loncastuximab_tesirine

    Participants in the clinical trial were also evaluated for side effects for the purpose of this drug application. [4] Trials were conducted at 28 sites in the United States, the United Kingdom, Italy, and Switzerland. [4] Loncastuximab tesirine was granted orphan drug designation by the FDA for the treatment of diffuse large B-cell lymphoma.