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  2. Beta3-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta3-adrenergic_agonist

    The β 3 (beta 3) adrenergic receptor agonist or β 3-adrenoceptor agonist, also known as β 3-AR agonist, are a class of medicine that bind selectively to β 3-adrenergic receptors. β 3 -AR agonists for the treatment of obesity and type 2 diabetes have been in developmental stages within many large pharmaceutical companies since the early ...

  3. Vibegron - Wikipedia

    en.wikipedia.org/wiki/Vibegron

    Vibegron is a selective agonist for the beta-3 adrenergic receptor. The receptors are located in the kidneys, urinary tract and bladder tissue. [20] Upon binding, the β3 receptor undergoes a conformational change. This induces the activation of adenylate cyclases via G proteins and thereby promotes the formation of cyclic adenosine ...

  4. Beta-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta-adrenergic_agonist

    Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing. [1] They are a class of sympathomimetic agents, each acting upon the beta adrenoceptors . [ 2 ]

  5. Mirabegron - Wikipedia

    en.wikipedia.org/wiki/Mirabegron

    Other significant side effects include urinary retention, irregular heart rate, and angioedema. [5] [7] It works by activating the β 3 adrenergic receptor in the bladder, resulting in its relaxation. [5] [7] Mirabegron is the first clinically available beta-3 agonist with approval for use in adults with overactive bladder. Mirabegron was ...

  6. Cardiotonic agent - Wikipedia

    en.wikipedia.org/wiki/Cardiotonic_agent

    They can be categorised into four distinct groups based on their unique mechanisms of action: cardiac glycosides, beta-adrenergic agonists, phosphodiesterase III inhibitors, and calcium sensitizers. It is important to note that certain medications, such as Milrinone and Digoxin , possess overlapping classifications due to their ability to ...

  7. Beta-3 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-3_adrenergic_receptor

    Some β 3 agonists have demonstrated antistress effects in animal studies, suggesting it also has a role in the central nervous system (CNS). β 3 receptors are found in the gallbladder, urinary bladder, and in brown adipose tissue. Their role in gallbladder physiology is unknown, but they are thought to play a role in lipolysis and ...

  8. Adrenergic blocking agent - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_blocking_agent

    Adrenergic blocking agents are a class of drugs that exhibit its pharmacological action through inhibiting the action of the sympathetic nervous system [1] in the body. The sympathetic nervous system(SNS) is an autonomic nervous system that we cannot control by will.

  9. Sympathomimetic drug - Wikipedia

    en.wikipedia.org/wiki/Sympathomimetic_drug

    Examples of sympathomimetic effects include increases in heart rate, force of cardiac contraction, and blood pressure. [1] The primary endogenous agonists of the sympathetic nervous system are the catecholamines (i.e., epinephrine [adrenaline], norepinephrine [noradrenaline], and dopamine ), which function as both neurotransmitters and hormones .

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