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Quieter sounds that are concentrated in a narrow frequency may also cause damage to specific frequency receptors. [1] The range of severity can vary from pain to hearing loss. [2] Acute acoustic trauma can be treated by combining hyperbaric oxygen therapy (HBO) with corticosteroids. Acute noise exposure causes inflammation and lower oxygen ...
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
In the setting of low ATP, it is more difficult for the muscle to relax, which causes the cycle to continue. Via a cascade of events, the activated pain neurons can cause neurogenic inflammation, which may lead to additional pain. In this way, a "vicious circle" is created. [7] [9] Pain from sound sometimes radiates to the face, scalp, and neck.
Ear pain, also known as earache or otalgia, is pain in the ear. [1] [2] Primary ear pain is pain that originates from the ear. Secondary ear pain is a type of referred pain, meaning that the source of the pain differs from the location where the pain is felt. Most causes of ear pain are non-life-threatening.
These drugs are known to cause headache, flushing and abnormal vision as their adverse effects. PDE-5 inhibitors are also known for inducing sudden sensorineural hearing loss. It is mainly related to the obstruction and dysfunction of eustachian tubes which affects middle-ear pressure.
Eustachian tube dysfunction can be caused by a number of factors. Some common causes include the flu, allergies, a cold, and sinus infections. [6] In patients with chronic ear disease such as cholesteatoma and chronic discharge, studies showed that they have obstructive pathology at the ear side of the Eustachian tube.
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