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Use during breastfeeding appears to be relatively safe. [7] It is a tricyclic antidepressant (TCA) and is believed to work by altering levels of serotonin and norepinephrine. [8] Nortriptyline was approved for medical use in the United States in 1964. [8] It is available as a generic medication. [7]
Breastfeeding and medications is the description of the medications that can be used by a breastfeeding mother, and the balance between maternal health and the safety of the breastfeeding infant. [1] [2] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities. [3]
The FDA issued a statement on July 19, 2006, stating nursing mothers on SSRIs must discuss treatment with their physicians. However, the medical literature on the safety of SSRIs has determined that some SSRIs like Sertraline and Paroxetine are considered safe for breastfeeding. [148] [149] [150]
Most of the weight gain caused by antidepressants is mild, with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs) per year on average.
Postpartum depression and breastfeeding failure are also attributed to neuroendocrine mechanisms. [5] Postpartum depression is also closely associated with inflammation caused by postpartum pain or sleep deprivation, which are common experiences of motherhood. Breastfeeding decreases this inflammation response which is beneficial to the mother ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
Tricyclic antidepressants are older antidepressants that, due to their side effect profiles, typically aren’t prescribed as first-line depression treatments today.
Most antidepressants, including SNRIs, are safe and effective in the geriatric population. The geriatric population is at greater risk for adverse effects relating to drug interaction as they are more likely to experience polypharmacy. [99] Decisions are often based on co-morbid conditions, drug interactions, and patient tolerance.
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