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Although such treatment can be costly, multiple studies have demonstrated that ATL in patients who have failed at least two anticonvulsant drug trials (thereby meeting the criteria for medically intractable temporal lobe epilepsy) has lower mortality, lower morbidity and lower long-term cost in comparison with continued medical therapy without ...
Temporal lobe resection acts as a treatment option for patients with temporal lobe epilepsy, or those whose seizure focus is in the temporal lobe. Temporal lobe seizures are the most common type (approximately 30% of diagnoses) of seizures for teens and young adults. [28] The procedure involves resecting, or cutting away, brain tissue within ...
A focal impaired awareness temporal lobe seizure occurs if a person becomes unaware during any part of the seizure. [10] Approximately 80% of seizures in the temporal lobe begin in the mesial temporal region, frequently starting in or around the hippocampus. The hippocampus, found in both temporal lobes, is essential for memory and learning. [12]
In 1825, Bouchet and Cazauvieilh described palpable firmness and atrophy of the uncus and medial temporal lobe of brains from epileptic and non-epileptic individuals. [4]: 565 In 1880, Wilhelm Sommer investigated 90 brains and described the classical Ammon's horn sclerosis pattern, severe neuronal cell loss in hippocampal subfield cornum Ammonis 1 (CA1) and some neuronal cell loss in ...
In addition, the chances of developing PTE differ by the location of the brain lesion: brain contusion that occurs on in one or the other of the frontal lobes has been found to carry a 20% PTE risk, while a contusion in one of the parietal lobes carries a 19% risk and one in a temporal lobe carries a 16% chance. [22]
Research shows that the most common areas to have focal lesions in non-penetrating traumatic brain injury are the orbitofrontal cortex (the lower surface of the frontal lobes) and the anterior temporal lobes, areas that are involved in social behavior, emotion regulation, olfaction, and decision-making, hence the common social/emotional and ...
The lobes of the brain most likely to be injured are the frontal and temporal lobes. [19] Other common locations for DAI include the white matter in the cerebral cortex, the superior cerebral peduncles, [16] basal ganglia, thalamus, and deep hemispheric nuclei.
In uncal herniation, a common subtype of transtentorial herniation, the innermost part of the temporal lobe, the uncus, can be squeezed so much that it moves towards the tentorium and puts pressure on the brainstem, most notably the midbrain. [8] The tentorium is a structure within the skull formed by the dura mater of the meninges.