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Elaborately gilded drug jar for storing mithridate. By Annibale Fontana, about 1580–1590.. Mithridate, also known as mithridatium, mithridatum, or mithridaticum, is a semi-mythical remedy with as many as 65 ingredients, used as an antidote for poisoning, and said to have been created by Mithridates VI Eupator of Pontus in the 1st century BC.
When cane sugar was an exotic Eastern commodity, the English recommended the sugar-based treacle as an antidote against poison, [7] originally applied as a salve. [8] By extension, treacle could be applied to any healing property: in the Middle Ages the treacle (i.e. healing) well at Binsey was a place of pilgrimage.
In keeping with most medical practices of his era, Mithridates' anti-poison routines included a religious component, supervised by the Agari, a group of Scythian shamans who never left him. [ 4 ] It has been suggested that Russian mystic Rasputin 's survival of a poisoning attempt was due to mithridatism, but this has not been proven.
The antidote for curare poisoning is an acetylcholinesterase (AChE) inhibitor (anti-cholinesterase), such as physostigmine or neostigmine. By blocking ACh degradation, AChE inhibitors raise the amount of ACh in the neuromuscular junction; the accumulated ACh will then correct for the effect of the curare by activating the receptors not blocked ...
To prevent serum sickness, it is often best to use an antitoxin obtained from the same species (e.g. use human antitoxin to treat humans). Most antitoxin preparations are prepared from donors with high titers of antibody against the toxin, making them hyperimmune globulins.
An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), "(medicine) given as a remedy".
Atropa bella-donna has a long history of use as a medicine, cosmetic, and poison. [14] [4] [15] Known originally under various folk names (such as "deadly nightshade" in English), the plant was named Atropa bella-donna by Carl Linnaeus (1707–1778) when he devised his classification system.
The Golden poison frog (Phyllobates terribilis) is among the species of poison frogs that have potential significance to medical research. Besides providing defense from predators, the toxins that poison frogs secrete interest medical researchers. Poison dart frogs, of the Dendrobatidae family, secrete batrachotoxin. This toxin has the ...