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The perichondrium (from Greek περί, peri, 'around' and χόνδρος, chondros, 'cartilage') is a layer of dense irregular connective tissue that surrounds the cartilage of developing bone. It consists of two separate layers: an outer fibrous layer and inner chondrogenic layer.
Cartilage is a resilient and smooth type of connective tissue. ... it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, ...
Within adults and developing adults, most chondroblasts are located in the perichondrium. This is a thin layer of connective tissue which protects cartilage and is where chondroblasts help to expand cartilage size whenever prompted to by hormones such as GH, TH, and glycosaminoglycans. [2]
Hyaline cartilage is located in the trachea, nose, epiphyseal plate, sternum, and ribs. [2] Hyaline cartilage is covered externally by a fibrous membrane known as the perichondrium. [2] The primary cells of cartilage are chondrocytes, which are in a matrix of fibrous tissue, proteoglycans and glycosaminoglycans. [2] [3]
This hyaline cartilage template expands through both: [8] [9] Interstitial growth Appositional growth Cellular protagonists: Chondrocytes present within the existing cartilage. Chondroblasts that develop from the perichondrium. Mechanism: Chondrocytes proliferate and lay down matrix. Chondroblasts differentiate into chondrocytes and lay down ...
Endochondral ossification is the process by which most vertebrate axial skeletons form into hardened bones from cartilage. This process begins with a cartilage anlage where chondrocyte cells will congregate and start their maturation process. Once the chondrocytes have fully matured at the desired rate, the cartilage tissue will harden into ...
A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele
The cartilage cells or chondrocytes are contained in cavities in the matrix, called cartilage lacunae; around these, the matrix is arranged in concentric lines as if it had been formed in successive portions around the cartilage cells. This constitutes the so-called capsule of the space.