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Corticosteroid, Pain medication [2] Radial neuropathy is a type of mononeuropathy which results from acute trauma to the radial nerve that extends the length of the arm. [ 3 ] It is known as transient paresthesia when sensation is temporarily abnormal.
Benzodiazepines, like many other sedative hypnotic drugs, cause apoptotic neuronal cell death. However, benzodiazepines do not cause as severe apoptosis to the developing brain as alcohol does. [105] [106] [107] The prenatal toxicity of benzodiazepines is most likely due to their effects on neurotransmitter systems, cell membranes and protein ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Severe symptoms usually occur as a result of abrupt or over-rapid withdrawal. Abrupt withdrawal can be dangerous and lead to excitotoxicity, causing damage and even death to nerve cells as a result of excessive levels of the excitatory neurotransmitter glutamate. Increased glutamatergic activity is thought to be part of a compensatory mechanism ...
CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2] These symptoms can impair activities of daily living, such as typing or dressing, reduce balance, and increase risk of falls and hospitalizations. They can also give cause to reduce or discontinue chemotherapy.
On the scale, which ranges from 0 for no pain to 10 for worst pain imaginable, patients treated with the drug showed reductions of 2.26, 2.11 and 2.18 at the high, mid and low doses, respectively.
One unusual cause of focal hyperalgesia is platypus venom. [5] Long-term opioid (e.g. heroin, morphine) users and those on high-dose opioid medications for the treatment of chronic pain may experience hyperalgesia and experience pain out of proportion to physical findings; this is a common cause for loss of efficacy of these medications over time.
Jeffrey Mogil, a professor of pain studies at McGill University in Canada, said: “For many decades it’s been standard medical practice to treat pain with anti-inflammatory drugs.