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n/a Ensembl ENSG00000181143 n/a UniProt Q8WXI7 n/a RefSeq (mRNA) NM_024690 NM_001401501 n/a RefSeq (protein) NP_078966 n/a Location (UCSC) Chr 19: 8.85 – 8.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins ...
CA-125 levels are not accurate in early stage ovarian cancer, as half of stage I ovarian cancer patients have a normal CA-125 level. [ 31 ] [ 29 ] CA-125 may also be elevated in benign (non-cancerous) conditions, including endometriosis , pregnancy , uterine fibroids , menstruation , ovarian cysts , systemic lupus erythematosus , liver disease ...
Guidelines from the American Society of Clinical Oncology discourage the use of CA19-9 as a screening test for cancer, particularly pancreatic cancer.The reason is that the test may be falsely normal (false negative) in many cases or abnormally elevated in people who have no cancer (false positive) in others.
The tumor marker CA-125 is frequently elevated in endometrial cancer and can be used to monitor response to treatment, particularly in serous cell cancer or advanced disease. [ 32 ] [ 44 ] [ 82 ] Periodic MRIs or CT scans may be recommended in advanced disease and women with a history of endometrial cancer should receive more frequent pelvic ...
State Route 125 (SR 125) is a state highway in the U.S. state of California that serves as a north–south route in San Diego County.It runs from SR 11 and SR 905 in Otay Mesa, near the Mexican border, to SR 52 in Santee.
CA-125: Mainly ovarian cancer, [13] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [14] Calcitonin: medullary thyroid carcinoma [15] Calretinin: mesothelioma, sex cord-gonadal stromal tumor, adrenocortical carcinoma, synovial sarcoma [9] Carcinoembryonic ...
Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion.CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth.
The CA-125 marker in children and adolescents can be frequently elevated even in absence of malignancy and conservative management should be considered. Polycystic ovarian syndrome involves the development of multiple small cysts in both ovaries due to an elevated ratio of leutenizing hormone to follicle stimulating hormone , typically more ...