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The mesothelium is a membrane composed of simple squamous epithelial cells of mesodermal origin, [2] which forms the lining of several body cavities: the pleura (pleural cavity around the lungs), peritoneum (abdominopelvic cavity including the mesentery, omenta, falciform ligament and the perimetrium) and pericardium (around the heart).
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (known as the mesothelium). [10] The area most commonly affected is the lining of the lungs and chest wall .
Cytology of normal mesothelium, with typical features. Wright's stain. The lateral plate mesoderm splits into the parietal (somatic) and visceral (splanchnic) layers. The formation of these layers starts with the appearance of intercellular cavities. [12] The somatic layer depends upon a continuous layer with mesoderm that covers the amnion.
Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath.. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (simple squamous epithelium) which produce the lubricating serous fluid.
Mesothelin is a 40 kDa protein that is expressed in mesothelial cells. [7] The protein was first identified by its reactivity with monoclonal antibody K1. [8] Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named ...
The coelom (or celom) [1] is the main body cavity in many animals [2] and is positioned inside the body to surround and contain the digestive tract and other organs.In some animals, it is lined with mesothelium.
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