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Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1]
The ascending reticular activating system (ARAS), also known as the extrathalamic control modulatory system or simply the reticular activating system (RAS), is a set of connected nuclei in the brains of vertebrates that is responsible for regulating wakefulness and sleep-wake transitions. The ARAS is in the midbrain reticular formation. [12]
Raichle coined the term "default mode" in 2001 to describe resting state brain function; [19] the concept rapidly became a central theme in neuroscience. [20] Around this time the idea was developed that this network of brain areas is involved in internally directed thoughts and is suspended during specific goal-directed behaviors.
Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. [4] Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to ...
PNNL scientists are studying the proteins involved in degenerative brain disorders. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to ...
The paramedian pontine reticular formation (PPRF) is a subset of neurons of the oral and caudal pontine reticular nuclei. With the abducens nucleus it makes up the horizontal gaze centre . [ 1 ] It is situated in the pons adjacent to the abducens nucleus . [ 2 ]
Reticular theory is an obsolete scientific theory in neurobiology that stated that everything in the nervous system, such as the brain, is a single continuous network. The concept was postulated by a German anatomist Joseph von Gerlach in 1871, and was most popularised by the Nobel laureate Italian physician Camillo Golgi .
Along with the oral pontine reticular nucleus, the midbrain reticular formation projects to the gigantocellular reticular nucleus. The midbrain reticular formation is the point at which the different algedonic signals come together, ensuring that the organism is aware of potential threats. [2]