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Ketamine potentiates the sedative effects of propofol [86] and midazolam. [87] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [88] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Ketamine’s antidepressant effects are part of what prompted researchers to explore other drugs that target glutamate—like the venerable cough suppressant dextromethorphan found in Robitussin ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
The main ingredient for the spray is esketamine hydrochloride, which is the “chemical cousin” of ketamine. ... Side effects include sleepiness, fainting, dizziness, anxiety, feeling ...
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NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Xylazine's muscle relaxant effect inhibits the transmission of neural impulses in the central nervous system. [17] In scientific research using animal experiments, xylazine is a component of the most common anesthetic, ketamine-xylazine (see: Rodent cocktail), to anesthetize rats, mice, hamsters, and guinea pigs. [18]
Although the FDA has approved ketamine for use as an anesthetic, infusion therapy hasn't been approved to treat chronic pain, depression, or other conditions. ... Lighter Side. Politics ...