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Aerobic respiration requires oxygen (O 2) in order to create ATP.Although carbohydrates, fats and proteins are consumed as reactants, aerobic respiration is the preferred method of pyruvate production in glycolysis, and requires pyruvate to the mitochondria in order to be oxidized by the citric acid cycle.
Each cycle of beta-oxidation shortens the fatty acid chain by two carbon atoms and produces one equivalent each of acetyl-CoA, NADH, and FADH 2. The acetyl-CoA is metabolized by the citric acid cycle to generate ATP, while the NADH and FADH 2 are used by oxidative phosphorylation to generate ATP. Dozens of ATP equivalents are generated by the ...
Glycolysis produces only 2 ATP molecules, but somewhere between 30 and 36 ATPs are produced by the oxidative phosphorylation of the 10 NADH and 2 succinate molecules made by converting one molecule of glucose to carbon dioxide and water, [6] while each cycle of beta oxidation of a fatty acid yields about 14 ATPs. These ATP yields are ...
Both the structure of ATP synthase and its underlying gene are remarkably similar in all known forms of life. ATP synthase is powered by a transmembrane electrochemical potential gradient, usually in the form of a proton gradient. In all living organisms, a series of redox reactions is used to produce a transmembrane electrochemical potential ...
Oxidative phosphorylation contributes the majority of the ATP produced, compared to glycolysis and the Krebs cycle. While the ATP count is glycolysis and the Krebs cycle is two ATP molecules, the electron transport chain contributes, at most, twenty-eight ATP molecules. A contributing factor is due to the energy potentials of NADH and FADH 2.
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The purine nucleotide cycle is used in times of glycolytic or ATP crisis, such as strenuous exercise or starvation. [ 14 ] [ 13 ] It produces fumarate , a citric acid cycle intermediate, which enters the mitochondrion through the malate-aspartate shuttle, and from there produces ATP by oxidative phosphorylation.
ATP contains one more phosphate group than ADP, while AMP contains one fewer phosphate group. Energy transfer used by all living things is a result of dephosphorylation of ATP by enzymes known as ATPases. The cleavage of a phosphate group from ATP results in the coupling of energy to metabolic reactions and a by-product of ADP. [1]