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However, these effects may be temporary and related to (1) incorrect placement of electrodes, (2) open-loop VS closed-loop stimulation, meaning a constant stimulation or an A.I. monitoring delivery system [80] and (3) calibration of the stimulator, so these side effects are potentially reversible.
Chemogenetics have been used in these fields to induce specific and reversible brain lesions and therefore, study specific activities of neuron population. Although chemogenetics offers specificity and high spatial resolution, it still faces some challenges when used in investigating neuropsychiatric disorders. Neuropsychiatric disorders ...
Generally, deep brain stimulation surgery is considered preferable to ablation because it has the same effect and is adjustable and reversible. [5] The advent of deep brain stimulation has been an important advance in the treatment of Parkinson's disease.
However, near this time in France and elsewhere, DBS was investigated as a substitute for lesioning of brain nuclei to control motor symptoms of movement disorders such as Parkinson's disease, and by the mid-1990s, this reversible, non-destructive stimulation therapy had become the primary application of DBS in appropriate patients, to slow ...
Mayberg is known in particular for her work delineating abnormal brain function in patients with major depression using functional neuroimaging. [1] [2] This work led to the first pilot study of deep brain stimulation (DBS), a reversible method of selective modulation of a specific brain circuit, for patients with treatment-resistant depression ...
In the case of an intention tremor, the thalamic nuclear region is targeted for treatment. This form of treatment causes reversible changes and does not cause any permanent lesions. Since it is reversible, deep brain stimulation is considered fairly safe. Reduction in tremor amplitude is almost guaranteed and sometimes resolved.