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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia . [ 2 ] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells . [ 2 ]
The presentation of patient with SPCD can be incredibly varied, from asymptomatic to lethal cardiac manifestations. [5] Early cases were reported with liver dysfunction, muscular findings (weakness and underdevelopment), hypoketotic hypoglycemia, cardiomegaly, cardiomyopathy and marked carnitine deficiency in plasma and tissues, combined with increased excretion in urine. [5]
SCD: sequential compression device sickle-cell disease sudden cardiac death SCI: spinal cord injury: SCID: severe combined immunodeficiency: SCIWORA: spinal cord injury without radiographic abnormality: SCLC: small cell lung cancer: SCN: severe congenital neutropenia sickle cell nephropathy superior cluneal nerves suprachiasmatic nucleus: scope ...
The diagnosis of acute chest syndrome is made difficult by its similarity in presentation with pneumonia. Both may present with a new opacification of the lung on chest x-ray. The presence of fevers, low oxygen levels in the blood, increased respiratory rate, chest pain, and cough are also common in acute chest syndrome.
Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors sickling of red blood ...
Paula Tanabe, a professor of nursing at Duke University, who has spent decades researching ways to improve care for sickle cell patients, said a confluence of factors adds to the racial bias ...
Cardiac arrest, also known as sudden cardiac arrest (SCA), [11] is when the heart suddenly and unexpectedly stops beating. [12][1] When the heart stops beating, blood cannot properly circulate around the body and the blood flow to the brain and other organs is decreased. When the brain does not receive enough blood, this can cause a person to ...
A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.