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Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia , and slurred speech.
Alprazolam, sold under the brand name Xanax among others, is a fast-acting, potent tranquilizer of moderate duration within the triazolobenzodiazepine group of chemicals called benzodiazepines. [15] Alprazolam is most commonly prescribed in the management of anxiety disorders , especially panic disorder and generalized anxiety disorder (GAD). [ 9 ]
A benzodiazepine can be placed into one of three groups by its elimination half-life, or time it takes for the body to eliminate half of the dose. [189] Some benzodiazepines have long-acting active metabolites, such as diazepam and chlordiazepoxide, which are metabolised into desmethyldiazepam. Desmethyldiazepam has a half-life of 36–200 ...
More young people are using Xanax – but overdose, addiction and side effects present serious risks. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: ...
Polydrug use involving benzodiazepines and alcohol can result in blackouts, increased risk-taking behaviour, and in severe cases seizures and overdose. [25] Those who use stimulant and depressant drugs are more likely to report adverse reactions from stimulant use, more likely to be injecting stimulants and more likely to have been treated for ...
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death .
Specifically, he had alprazolam — the active ingredient in Xanax — and alcohol in his blood, both at such low levels that Dr. Christopher Young, Ventura County’s chief medical examiner, said ...
As of 2016, benzodiazepines were most likely to cause fatal overdose in Australia, [20] with diazepam (Valium) being the drug most responsible. [12] While fatal overdoses are highly associated with drugs such as opiates, cocaine and alcohol, [ 2 ] deaths from other drugs such as caffeine are extremely rare.