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  2. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    In this select population who are naive to and overdose solely on a benzodiazepine, it can be considered. [53] Due to its short half life, the duration of action of flumazenil is usually less than 1 hour, and multiple doses may be needed. [48] When flumazenil is indicated the risks can be reduced or avoided by slow dose titration of flumazenil ...

  3. Benzodiazepine use disorder - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_use_disorder

    Benzodiazepines can induce a severe benzodiazepine withdrawal syndrome as well as drug seeking behavior. Sedative -hypnotics such as alcohol , benzodiazepines, and the barbiturates are known for the severe physical dependence that they are capable of inducing which can result in severe withdrawal effects. [ 13 ]

  4. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Polydrug use involving benzodiazepines and alcohol can result in an increased risk of blackouts, risk-taking behaviours, seizures, and overdose. [223] Dependence and tolerance, often coupled with dosage escalation, to benzodiazepines can develop rapidly among people who misuse drugs; withdrawal syndrome may appear after as little as three weeks ...

  5. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.

  6. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    A protracted withdrawal syndrome can occur with symptoms persisting for months to years after cessation of substance use. Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and ...

  7. Benzodiazepine dependence - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_dependence

    Abrupt withdrawal from any of these compounds, e.g., barbiturates, benzodiazepines, alcohol, corticosteroids, neuroactive steroids, and nonbenzodiazepines, precipitate similar withdrawal effects characterized by central nervous system hyper-excitability, resulting in symptoms such as increased seizure susceptibility and anxiety. [33]

  8. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Long-term use of benzodiazepines can induce perceptual disturbances and depersonalization in some people, even in those taking a stable daily dosage, and it can also become a protracted withdrawal feature of the benzodiazepine withdrawal syndrome. [54] In addition, chronic use of benzodiazepines is a risk factor for blepharospasm. [55]

  9. Alprazolam - Wikipedia

    en.wikipedia.org/wiki/Alprazolam

    Xanax 0.25 mg. (top row), 0.5 mg. (middle row), and 1 mg. (bottom row) tablets. The maximum recommended daily dose is 10 milligrams per day. [9] Overdoses of alprazolam can be mild to severe depending on the quantity ingested and if other drugs are taken in combination. [65] Alprazolam overdoses cause excess central nervous system (CNS ...