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Extreme degrees of asphyxia can cause cardiac arrest and death. If resuscitation is successful, the infant is usually transferred to a neonatal intensive care unit. There has long been a scientific debate over whether newborn infants with asphyxia should be resuscitated with 100% oxygen or normal air. [3]
Although total liquid ventilation (TLV) with completely liquid-filled lungs can be beneficial, [9] the complex liquid-filled tube system required is a disadvantage compared to gas ventilation—the system must incorporate a membrane oxygenator, heater, and pumps to deliver to, and remove from the lungs tidal volume aliquots of conditioned perfluorocarbon (PFC).
Meconium aspiration syndrome (MAS), also known as neonatal aspiration of meconium, is a medical condition affecting newborn infants. It describes the spectrum of disorders and pathophysiology of newborns born in meconium-stained amniotic fluid (MSAF) and have meconium within their lungs. Therefore, MAS has a wide range of severity depending on ...
High-frequency oscillatory ventilation was first described in 1972 [8] and is used in neonates and adult patient populations to reduce lung injury, or to prevent further lung injury. [9] HFOV is characterized by high respiratory rates between 3.5 and 15 hertz (210 - 900 breaths per minute) and having both inhalation and exhalation maintained by ...
Surfactant medications can decrease the risk of death for very low-birth-weight infants who are hospitalized by 30%. [28] Such small premature infants may remain ventilated for months. A study shows that an aerosol of a perfluorocarbon such as perfluoromethyldecalin can reduce inflammation in swine model of IRDS. [29]
A liquid ventilator is similar to a medical ventilator except that it should be able to ensure reliable total liquid ventilation with a breatheable liquid (a perfluorocarbon). [ 1 ] [ 2 ] Liquid ventilators are prototypes that may have been used for animal experimentations but experts recommend continued development of a liquid ventilator ...
Pulmonary aspiration is the entry of solid or liquid material such as pharyngeal secretions, food, drink, or stomach contents from the oropharynx or gastrointestinal tract, into the trachea and lungs. [1] When pulmonary aspiration occurs during eating and drinking, the aspirated material is often colloquially referred to as "going down the ...
Neonatal resuscitation, also known as newborn resuscitation, is an emergency procedure focused on supporting approximately 10% of newborn children who do not readily begin breathing, putting them at risk of irreversible organ injury and death. [1] Many of the infants who require this support to start breathing well on their own after assistance.