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  2. 3β-Hydroxysteroid dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/3β-hydroxysteroid...

    3β-Hydroxysteroid dehydrogenase/Δ 5-4 isomerase (3β-HSD) (EC 1.1.1.145) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

  3. 17β-Hydroxysteroid dehydrogenase III deficiency - Wikipedia

    en.wikipedia.org/wiki/17β-Hydroxysteroid...

    Androstenedione is created from dehydroepiandrosterone (DHEA) or 17-hydroxyprogesterone. [ 10 ] A deficiency in the HSD17B3 gene is characterized biochemically by decreased levels of testosterone which results in the insufficient formation of dihydrotestosterone during fetal development.

  4. Androstenediol - Wikipedia

    en.wikipedia.org/wiki/Androstenediol

    Androstenediol, or 5-androstenediol (abbreviated as A5 or Δ 5-diol), also known as androst-5-ene-3β,17β-diol, is an endogenous weak androgen and estrogen steroid hormone and intermediate in the biosynthesis of testosterone from dehydroepiandrosterone (DHEA). It is closely related to androstenedione (androst-4-ene-3,17-dione).

  5. Congenital adrenal hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia

    If CAH is caused by the deficiency of the 21-hydroxylase enzyme, then treatment aims to normalize levels of androstenedione, but normalization of 17α-hydroxyprogesterone is a sign of overtreatment. [32] Treatment can be monitored by measuring androstenedione and 17α-hydroxyprogesterone levels in blood or saliva. [32]

  6. Androstenedione - Wikipedia

    en.wikipedia.org/wiki/Androstenedione

    Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ 4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

  7. Adrenal steroid - Wikipedia

    en.wikipedia.org/wiki/Adrenal_steroid

    Adrenal steroids such as glucocorticoids and mineralocorticoids are commonly used as treatments in diseases such as Congenital adrenal hyperplasia. [2] CAH commonly causes overproduction of androgens, glucocorticoid treatment is used to reduce Adrenocorticotropic hormone (ACTH) and reduce the production of androgens allowing for symptoms of CAH to be managed though treatment is required to be ...

  8. Androstenetriol - Wikipedia

    en.wikipedia.org/wiki/Androstenetriol

    Androstenetriol (AET, androst-5-ene-3β,7β,17β-triol, β-androstenetriol, or β-AET) is a steroid produced in the adrenal glands as a metabolite of dehydroepiandrosterone (DHEA). [1] It is believed to have similar effects as DHEA and androstenediol . [ 2 ]

  9. 5-Androstenedione - Wikipedia

    en.wikipedia.org/wiki/5-Androstenedione

    5-Androstenedione, also known as androst-5-ene-3,17-dione, is a prohormone of testosterone. The World Anti-Doping Agency prohibits its use in athletes. In the United States, it is a controlled substance. 5-Androstenedione is structurally similar to 4-androstenedione, with the exception of the position of a carbon-carbon double bond.

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