Ad
related to: treatment of necrosis of the jaw areaamazon.com has been visited by 1M+ users in the past month
Search results
Results From The WOW.Com Content Network
A diagnosis of bisphosphonate-associated osteonecrosis of the jaw relies on three criteria: [6] the patient possesses an area of exposed bone in the jaw persisting for more than 8 weeks, the patient must present with no history of radiation therapy to the head and neck; the patient must be taking or have taken bisphosphonate medication.
Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature.
OM may occur by direct inoculation of pathogens into the bone (through surgery or injury), by spread of an adjacent area of infection or by seeding of the infection from a non adjacent site via the blood supply (hematogenous spread). Unlike OM of the long bones, hematogenous OM in the bones of the jaws is rare. OM of the jaws is mainly caused ...
Phossy jaw, formally known as phosphorus necrosis of the jaw, was an occupational disease affecting those who worked with white phosphorus (also known as yellow phosphorus) without proper safeguards. It is also likely to occur as the result of use of chemical weapons that contain white phosphorus.
The symptoms are necrosis of the mandible (lower jawbone) and the maxilla (upper jaw), constant bleeding of the gums, and (usually) after some time, severe distortion due to bone tumors and porosity of the lower jaw. Symptoms also include soreness throughout the body, significant decrease in body weight and loss of teeth.
Collagenase (breakdown of collagen) in the jaw bone leads to bone degeneration, providing room for cysts to develop. Substances released by the body's immune system as a result of the connective tissue breakdown, such as cytokines and growth factors, contribute to the mobilization and proliferation of epithelial cells in the area.
Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. [1] ORN occurs most commonly in the mouth during the treatment of head and neck cancer, and can arise over 5 years after radiation. [2]
Neuralgia-inducing cavitational osteonecrosis (NICO) is a diagnosis whereby a putative jawbone cavitation causes chronic facial neuralgia; this is different from osteonecrosis of the jaw. [1] In NICO the pain is said to result from the degenerating nerve ("neuralagia"). [2] [3] [1] The condition is probably rare, if it does exist. [4]