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  2. E/A ratio - Wikipedia

    en.wikipedia.org/wiki/E/A_ratio

    The reversal of the E/A ratio ('A' velocity becomes greater than 'E' velocity) is often accepted as a clinical marker of diastolic dysfunction, in which the left ventricular wall becomes so stiff as to impair proper filling, which can lead to diastolic heart failure. This can occur, for instance, with longstanding untreated hypertension.

  3. Diastolic function - Wikipedia

    en.wikipedia.org/wiki/Diastolic_function

    In clinical cardiology the term "diastolic function" is most commonly referred as how the heart fills. [1] Parallel to "diastolic function", the term " systolic function" is usually referenced in terms of the left ventricular ejection fraction (LVEF), which is the ratio of stroke volume and end-diastolic volume . [ 2 ]

  4. Heart failure with preserved ejection fraction - Wikipedia

    en.wikipedia.org/wiki/Heart_failure_with...

    Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.

  5. Ejection fraction - Wikipedia

    en.wikipedia.org/wiki/Ejection_fraction

    Modalities applied to measurement of ejection fraction is an emerging field of medical mathematics and subsequent computational applications. The first common measurement method is echocardiography, [7] [8] although cardiac magnetic resonance imaging (MRI), [8] [9] cardiac computed tomography, [8] [9] ventriculography and nuclear medicine (gated SPECT and radionuclide angiography) [8] [10 ...

  6. Fourth heart sound - Wikipedia

    en.wikipedia.org/wiki/Fourth_heart_sound

    The fourth heart sound or S 4 is an extra heart sound that occurs during late diastole, immediately before the normal two "lub-dub" heart sounds (S 1 and S 2).It occurs just after atrial contraction and immediately before the systolic S 1 and is caused by the atria contracting forcefully in an effort to overcome an abnormally stiff or hypertrophic ventricle.

  7. An alarming number of adults in the U.S. are at risk of ... - AOL

    www.aol.com/news/surprisingly-high-number-adults...

    Nearly 90% of adults over age 20 in the U.S. are at risk of developing heart disease, an alarming new study suggests. ... heart failure and stroke, Aggarwal said. “We need to diagnose earlier ...

  8. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    Diastolic dysfunction is associated with a reduced compliance, or increased stiffness, of the ventricle wall. This reduced compliance results in an inadequate filling of the ventricle and a decrease in the end-diastolic volume. The decreased end-diastolic volume then leads to a reduction in stroke volume because of the Frank-Starling mechanism. [1]

  9. Diabetic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_cardiomyopathy

    Defects in cellular processes such as autophagy and mitophagy are thought to contribute to the development of diabetic cardiomyopathy. [2] Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function [5] in the presence of a diastolic dysfunction.