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Topiramate can cause birth defects, including cleft lip and palate. [12] Risks/benefits should be carefully discussed with the full treatment team. Topiramate is considered "probably compatible" with lactation and is not contraindicated for breastfeeding, though monitoring of the infant for diarrhea or poor weight gain may be considered.
Two new studies suggest once again the importance of getting a good night's sleep for good health over a lifetime, as scientists pursue new understandings of restorative deep sleep.
Importantly, the glymphatic system is only on during the deep part of sleep called non-REM sleep. This is because of a neuromodulator called norepinephrine , which during non-REM sleep is released ...
Phentermine and topiramate can cause fetal harm. Data from pregnancy registries and epidemiology studies indicate that a fetus exposed to topiramate in the first trimester of pregnancy has an increased risk of oral clefts (cleft lip with or without cleft palate). [ 3 ]
Sleep can be adversely affected by benzodiazepine dependence. Possible adverse effects on sleep include induction or worsening of sleep disordered breathing. Like alcohol, benzodiazepines are commonly used to treat insomnia in the short term (both prescribed and self-medicated), but worsen sleep in the long term.
Acute kidney injury is when the kidneys suddenly stop working properly or fail altogether. ... Getting enough sleep. Sleep is good for your energy levels, mood, mental health, and even weight loss ...
Sleep deprivation can have a negative impact on mood. [55] Staying up all night or taking an unexpected night shift can make one feel irritable. Once one catches up on sleep, one's mood will often return to baseline or normal. Even partial sleep deprivation can have a significant impact on mood.
Improvement to cognitive performance caused by exercise could last for 24 hours, a new study shows. Scientists also linked getting 6 or more hours of sleep to better memory test scores the next day.