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The power of twin designs arises from the fact that twins may be either identical (monozygotic (MZ), i.e. developing from a single fertilized egg and therefore sharing all of their polymorphic alleles) or fraternal (dizygotic (DZ), i.e. developing from two fertilized eggs and therefore sharing on average 50% of their alleles, the same level of genetic similarity found in non-twin siblings).
A twin study compares the concordance rate of identical twins to that of fraternal twins. This can help suggest whether a disease or a certain trait has a genetic cause. [3] Controversial uses of twin data have looked at concordance rates for homosexuality and intelligence. Other studies have involved looking at the genetic and environmental ...
Identical or monozygotic twins share their genes, while fraternal or dizygotic twins are only as genetically similar as any other sibling pair. When twins both share a trait, they are concordant for this trait; and when they differ they are discordant. If identical twins have a higher rate of concordance for a trait than fraternal twins, it ...
A second and more common design is the twin study in which the similarity of identical and fraternal twins is used to estimate heritability. These studies can be limited by the fact that identical twins are not completely genetically identical, potentially resulting in an underestimation of heritability.
The study was subsequently the subject of Identical Strangers, a 2007 memoir by separated identical twins Elyse Schein and Paula Bernstein [11] (who appear in the film), as well as the 2017 documentary The Twinning Reaction [12] and a 2018 episode of the American TV news program 20/20 titled "Secret Siblings". [13]
Our bodies have 3 billion genetic building blocks, or base pairs, that make us who we are. And of those 3 billion base pairs, only a tiny amount are unique to us, making us about 99.9% genetically ...
There is evidence of heritability in personality traits. For example, one study found that approximately half of personality differences in high-school aged fraternal and identical twins were due to genetic variation - and another study suggests that no one personality trait is more heritable than another. [6] [8]
Sophie and Adrian are cousins, but also genetic siblings known as quaternary twins. Quaternary twins occur when one set of identical twins has children with another set of identical twins.