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In modern times, the name "Manila" is commonly used to refer to the entire metropolitan area, the greater metropolitan area, and the city proper. Metro Manila , the officially defined metropolitan area, is the capital region of the Philippines, and includes the much larger Quezon City and the Makati Central Business District .
In epidemiology, a pandemic is defined as "an epidemic occurring over a very wide area, crossing international boundaries, and usually affecting a large number of people". During the COVID-19 pandemic, as with other pandemics, the meaning of this term has been challenged.