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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels.
Gastric worms (O. tricuspis) are not covered by any of these active substances; here, no preparations approved for cats are on the market in Germany, so that other veterinary drugs based on levamisole or ivermectin have to be repurposed. In the case of kidney worm infestation (D. renale), only removal of the affected kidney is possible.
Levamisole was originally used as an anthelmintic to treat worm infestations in both humans and animals. Levamisole works as a nicotinic acetylcholine receptor agonist that causes continued stimulation of the parasitic worm muscles, leading to paralysis. [8]
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
In dogs and cats, whose gastrointestinal tracts are infected with the tapeworms Dipylidium caninum or Taenia taeniaeformis, respectively; [11] [12] praziquantel is also often used in fixed combination with pyrantel embonate against the roundworms : Toxocara cati and Toxascaris leonina.