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Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Cases of whooping cough are surging across the country. Doctors share symptoms, how to prevent pertussis, vaccination information, and treatments amid outbreak. What Doctors Want You to Know About ...
Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). [1] [2] There are two main types: whole-cell vaccines and acellular vaccines.[1] [2] The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective.
The DPT vaccine or DTP vaccine is a class of combination vaccines to protect against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus (lockjaw). [7] The vaccine components include diphtheria and tetanus toxoids , and either killed whole cells of the bacterium that causes pertussis or pertussis antigens .
European countries have reported a surge in whooping cough cases in 2023 and the first quarter of 2024, with 10 times as many identified as in each of the previous two years. In total, nearly ...
One is pertussis, also called whooping cough, and the Massachusetts Department of Public Health reports a fivefold increase statewide in the number of confirmed cases, with 754 so far this year ...
Pertussis was well known throughout Europe by the middle of the 18th century. Jules Bordet and Octave Gengou described in 1900 the finding of a new “ovoid bacillus” in the sputum of a 6-month-old infant with whooping cough. They were also the first to cultivate Bordetella pertussis at the Pasteur Institute in Brussels in 1906. [9]
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .