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  2. Chloral hydrate - Wikipedia

    en.wikipedia.org/wiki/Chloral_hydrate

    Chloral hydrate is a geminal diol with the formula Cl 3 C−CH(OH) 2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer and more effective alternatives but it remained in usage in the United States until at least the 1970s. [ 4 ]

  3. Hypnotic - Wikipedia

    en.wikipedia.org/wiki/Hypnotic

    Research about using medications to treat insomnia evolved throughout the last half of the 20th century. Treatment for insomnia in psychiatry dates back to 1869, when chloral hydrate was first used as a soporific. [12] Barbiturates emerged as the first class of drugs in the early 1900s, [13] after which chemical substitution allowed derivative ...

  4. Dimenhydrinate - Wikipedia

    en.wikipedia.org/wiki/Dimenhydrinate

    Diphenhydramine is the primary constituent of dimen­hydrinate and dictates the primary effect. The main differences relative to pure diphen­hydramine are a lower potency due to being combined with 8-chloro­theo­phylline (by weight, dimen­hydrinate is between 53% and 55.5% diphen­hydramine) [10] and the fact that the stimulant properties of 8-chloro­theo­phylline help reduce the side ...

  5. Ethchlorvynol - Wikipedia

    en.wikipedia.org/wiki/Ethchlorvynol

    Ethchlorvynol is a member of the class of sedative-hypnotic carbinols, which includes methylparafynol and tert-amyl alcohol.It is not a benzodiazepine, carbamate, or barbituric acid derivative, and its molecular structure is considerably simpler.

  6. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin is also available as an over-the-counter dietary supplement in many countries. It is available in both immediate-release and less commonly prolonged-release forms. The compound is available in supplements at doses ranging from 0.3 mg to 10 mg or more. It is also possible to buy raw melatonin powder by the weight. [39]

  7. Pentobarbital - Wikipedia

    en.wikipedia.org/wiki/Pentobarbital

    [12] [13] The oral dosage of pentobarbital indicated for physician-assisted suicide in Oregon is typically 10 g of liquid. [12] [13] In Switzerland, sodium pentobarbital is administered to the patient intravenously. Once administered, sleep is induced within 30 seconds, and the heart stops beating within 3 minutes. [14] Oral administration is ...