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Advocates of coffee enemas often point to their inclusion in editions of the Merck Manual through 1972, where coffee is listed as an ingredient for a retention enema for treating constipation. The Merck Manual does not list any other uses for coffee enemas, and in editions after 1972 all mention of them was dropped. [8]
A 2011 review found tentative evidence that green coffee extract promotes weight loss; however, the quality of the evidence was poor. [1] [4] [5] A larger 2017 review assessed the effects of chlorogenic acid, the main phenolic compound in green coffee extract, determining that human studies to date were of poor quality and that no conclusions could be drawn from them.
The health effects of coffee include various possible health benefits and health risks. [ 1 ] A 2017 umbrella review of meta-analyses found that drinking coffee is generally safe within usual levels of intake and is more likely to improve health outcomes than to cause harm at doses of 3 or 4 cups of coffee daily.
Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubricant, and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances. Sufficiently high doses of laxatives may cause diarrhea.
Caffeine dependence can cause a host of physiological effects if caffeine consumption is not maintained. Withdrawal symptoms may include headaches, fatigue, difficulty concentrating, lack of motivation, mood swings, nausea, insomnia, dizziness, cardiac issues, hypertension, anxiety, backaches, and joint pain; these can range in severity from mild to severe. [18]
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The most common side effects of these drugs that led to withdrawals were mental disturbances, cardiac side effects, and drug abuse or drug dependence. Deaths were associated with seven products. [84] Ephedra was removed from the US market in 2004 over concerns that it raises blood pressure and could lead to strokes and death. [85]
Certain enema preparations have been associated with heart attacks and electrolyte imbalances, and improperly prepared or used equipment can cause infection or damage to the bowel. Frequent colon cleansing can lead to dependence on enemas to defecate and some herbs may reduce the effectiveness of, or increase the risks associated with the use ...