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Fluconazole is an inhibitor of the human cytochrome P450 system, particularly the isozyme CYP2C19 (CYP3A4 and CYP2C9 to lesser extent) [31] In theory, therefore, fluconazole decreases the metabolism and increases the concentration of any drug metabolised by these enzymes.
Athlete's foot, known medically as tinea pedis, is a common skin infection of the feet caused by a fungus. [2] Signs and symptoms often include itching, scaling, cracking and redness. [3] In rare cases the skin may blister. [6] Athlete's foot fungus may infect any part of the foot, but most often grows between the toes. [3]
Ketoconazole is majorly used topically to treat fungal skin infections such as tinea pedis (Athlete's foot), seborrhoeic dermatitis, dandruff, and pityriasis versicolor. It can also be used to prevent the recurrence of fungal infections. The drug comes in the form of creams, shampoos, and tablets.
Podiatrists explain what athlete’s foot is, how people get athlete’s foot and how to prevent it. They also share over-the-counter treatments for athlete’s foot that can help get rid of it.
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
A 2003 survey of diseases of the foot in 16 European countries found onychomycosis to be the most frequent fungal foot infection and estimated its prevalence at 27%. [43] [44] Prevalence was observed to increase with age. In Canada, the prevalence was estimated to be 6.48%. [45]
Trichophyton rubrum is one of the most common causes of chronic tinea pedis commonly known as athlete's foot. [12] Chronic infections of tinea pedis result in moccasin foot, in which the entire foot forms white scaly patches and infections usually affect both feet. [10] Individuals with tinea pedis are likely to have infection at multiple sites ...
Toe nails become infected with fungi in the same way as the rest of the foot, typically by being trapped with fungi in the warm, dark, moist inside of a shoe. Fungal infection of the nails is called tinea unguium, and is not included in the medical definition of "athlete's foot", even though toe nails are part of the foot. Fungi are more ...