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Two reviews in people with blood cancers receiving intensive chemotherapy or a stem cell transplant found that overall giving platelet transfusions when the platelet count is less than 10 x 10 9 /L compared to giving platelet transfusions when the platelet count is less than 20 or 30 x 10 9 /L had no effect on the risk of bleeding. [14] [18]
In a typical set of rules, a platelet donor must weigh at least 50 kg (110 lb) and have a platelet count of at least 150 x 10 9 /L (150,000 platelets per mm³). [2] One unit has greater than 3×10 11 platelets. Therefore, it takes 2 liters of blood having a platelet count of 150,000/mm³ to produce one unit of platelets.
Transfusion of a single unit also encourages less wastage of blood products [5] and can be cost-effective. Single unit transfusion can be as part of an institutional or national guidelines [3] and instituted with the help of a transfusion committee or transfusion practitioner. Education of medical staff is important and catch phrases such as ...
The first blood transfusion from animal to human was administered by Dr. Jean-Baptiste Denys, eminent physician to King Louis XIV of France, on June 15, 1667. [82] He transfused the blood of a sheep into a 15-year-old boy, who survived the transfusion. [83] Denys performed another transfusion into a labourer, who also survived.
Blood compatibility testing is routinely performed before a blood transfusion.The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for incompatibility.
An exchange transfusion is a blood transfusion in which the patient's blood or components of it are exchanged with (replaced by) other blood or blood products. [1] The patient's blood is removed and replaced by donated blood or blood components. This exchange transfusion can be performed manually or using a machine . [2] Most blood transfusions ...
Hematology (spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. [1] [2] It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, bone marrow ...
Platelet transfusions are generally not recommended. [6] About 1 per 100,000 people are affected. [3] Onset is typically in adulthood and women are more often affected. [3] About 10% of cases begin in childhood. [3] The condition was first described by Eli Moschcowitz in 1924. [3] The underlying mechanism was determined in the 1980s and 1990s. [3]