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Substituted and dehydro derivatives of 4-piperidinone are intermediates in alkaloid syntheses. [1] The N-protonated derivative is typically isolated as the hydrate (HO) 2 C(CH 2) 4 NH + 2. [2] It is a List I chemical in the United States as it is a precursor to fentanyl. Fentanyl synthesis using the Gupta method starting from 4-piperidone
Boiling point (°C) K b (°C⋅kg/mol) Freezing point (°C) K f (°C⋅kg/mol) Data source; Aniline: 184.3 3.69 –5.96 –5.87 K b & K f [1] Lauric acid: 298.9 44 –3.9 Acetic acid: 1.04 117.9 3.14 16.6 –3.90 K b [1] K f [2] Acetone: 0.78 56.2 1.67 –94.8 K b [3] Benzene: 0.87 80.1 2.65 5.5 –5.12 K b & K f [2] Bromobenzene: 1.49 156.0 6. ...
This page contains tables of azeotrope data for various binary and ternary mixtures of solvents. The data include the composition of a mixture by weight (in binary azeotropes, when only one fraction is given, it is the fraction of the second component), the boiling point (b.p.) of a component, the boiling point of a mixture, and the specific gravity of the mixture.
N-Methyl-3-piperidyl benzilate (JB-336, BZ) Piperidine is also commonly used in chemical degradation reactions, such as the sequencing of DNA in the cleavage of particular modified nucleotides . Piperidine is also commonly used as a base for the deprotection of Fmoc - amino acids used in solid-phase peptide synthesis .
Melting point: 150 °C (302 °F; 423 K) Boiling point: ... 4-Piperidone; Dehydroacetic acid; References This page was last edited on 14 June 2024, at 18:14 (UTC ...
This is a list of the various reported boiling points for the elements, with recommended values to be used elsewhere on Wikipedia. ... 3930 °C: 7 N nitrogen (N 2 ...
4-Methylpyridine is the organic compound with the formula CH 3 C 5 H 4 N. It is one of the three isomers of methylpyridine. This pungent liquid is a building block for the synthesis of other heterocyclic compounds. Its conjugate acid, the 4-methylpyridinium ion, has a pK a of 5.98, about 0.7 units above that of pyridine itself. [1]
2,2,6,6-Tetramethylpiperidine, abbreviated TMP, HTMP, or TMPH, is an organic compound of the amine class. In appearance, it is a colorless liquid and has a "fishy", amine-like odor.