Search results
Results From The WOW.Com Content Network
Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and over the counter. [2] [4] In 2022, it was the 291st most commonly prescribed medication in the United States, with more than 400,000 prescriptions. [5] [6]
Voglibose was discovered in 1981, and was first launched in Japan in 1994, [2] under the trade name BASEN, to improve postprandial hyperglycemia in diabetes mellitus. [3] Postprandial hyperglycemia (PPHG) is primarily due to first phase insulin secretion. Alpha glucosidase inhibitors delay glucose absorption at the intestine level and thereby ...
Aldose reductase activity increases as the glucose concentration rises in diabetes in those tissues that are not insulin sensitive, which include the lenses, peripheral nerves, and glomerulus. Sorbitol does not diffuse through cell membranes easily and therefore accumulates, causing osmotic damage which leads to retinopathy and neuropathy .
Hydroxyzine can also be used for the treatment of allergic conditions, such as chronic urticaria, atopic or contact dermatoses, and histamine-mediated pruritus. [ medical citation needed ] These have also been confirmed in both recent and past studies to have no adverse effects on the liver, blood, nervous system, or urinary tract.
Alimemazine , also known as trimeprazine, commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). [3] It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness.
Type 3 diabetes is a proposed pathological linkage between Alzheimer's disease and certain features of type 1 and type 2 diabetes. [1] Specifically, the term refers to a set of common biochemical and metabolic features seen in the brain in Alzheimer's disease, and in other tissues in diabetes; [1] [2] it may thus be considered a "brain-specific type of diabetes."
These effects were significantly better in those with poorer control of diabetes. [9] A systematic review and metaanalysis showed that based on the results of 10 articles, it can be concluded that Epalrestat has some benefit in the control of diabetic cardiovascular autonomic neuropathy but only in the early or mild cases.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]