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Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, [ 1 ] including as a consequence of medical device implantation.
Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue, [1] [2] causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. [3]
Monckeberg's calcification typically occurs near the internal elastic lamina or, less frequently, in the media of muscular arteries without alterations in calcium metabolism. Its clinical importance is not yet fully understood. Some recent studies suggest a connection between Monckeberg's calcification and metabolic vascular calcification.
Dystrophic calcinosis cutis is the most prevalent kind of calcification on the skin. [2] The ectopic calcified mass usually consists of amorphous calcium phosphate and hydroxyapatite. [6] Dystrophic calcification is linked to a number of illnesses, such as infections, hereditary diseases, cutaneous neoplasms, and connective tissue diseases. [7]
Metastatic calcification involves a systemic calcium excess imbalance, which can be caused by hypercalcemia, kidney failure, milk-alkali syndrome, lack or excess of other minerals, or other causes. Tumoral calcinosis
Chondrocalcinosis or cartilage calcification is calcification (accumulation of calcium salts) in hyaline cartilage and/or fibrocartilage. [1] Chondrocalcinosis is an observation that can be visualized through diagnostic imaging tests such as X-rays , CT , MRI , and ultrasound .
Calcification due to degenerative changes in the epithelial cell rests of Malassez [5] Calcification of thrombosed (blocked) capillaries in the periodontal ligament [ 5 ] (i.e. a phlebolith ) [ 6 ] Microtrauma to Sharpey's fibres [ 2 ] causes small spicules of cementum or alveolar bone to splinter into the periodontal membrane [ 4 ] Some do not ...
Arterial calcification due to CD73 deficiency or Calcification of joints and arteries is a rare genetic disorder affecting adults. [1] Signs and symptoms