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Psilocybe azurescens is a species of psychedelic mushroom whose main active compounds are psilocybin and psilocin.It is among the most potent of the tryptamine-bearing mushrooms, containing up to 1.8% psilocybin, 0.5% psilocin, and 0.4% baeocystin by dry weight, averaging to about 1.1% psilocybin and 0.15% psilocin.
Recreational doses of psilocybin mushrooms are typically between 1.0 to 3.5–5.0 g of dry mushrooms and 10 to 50 g of fresh mushrooms. [ 48 ] [ 51 ] This corresponds to a dosage of psilocybin of about 10 to 50 mg. [ 51 ] Usual doses of the common species P. cubensis range around 1.0 to 2.5 g, while about 2.5 to 5.0 g dried mushroom material is ...
Psilocybin comprises approximately 1% of the weight of Psilocybe cubensis mushrooms, and so nearly 1.7 kilograms (3.7 lb) of dried mushrooms, or 17 kilograms (37 lb) of fresh mushrooms, would be required for a 60-kilogram (130 lb) person to reach the 280 mg/kg LD 50 value of rats. [56]
North American fruiting bodies of P. cyanescens have been shown to have between 0.66% and 1.96% total indole content by dry weight. [20] European fruiting bodies have been shown to have between 0.39% and 0.75% total indole content by dry weight. [6] North American specimens of P. cyanescens are among the most potent of psychedelic mushrooms.
Using the technique of paper chromatography, Hofmann confirmed the presence of 0.25% (by weight) psilocybin in dried samples. Their 1963 publication was the first report of psilocybin in a European mushroom species; previously, it had been known only in Psilocybe species native to Mexico, Asia and North America. [33]
While Amanita mushrooms are unscheduled in the United States, the sale of Amanita products exists in a legal gray area as they are listed as a poison by the FDA. [99] Amanita mushrooms and muscimol are not approved as an ingredient in food or dietary supplements, [ 100 ] with some drawing comparisons to the controversial legal status of hemp ...
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