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  2. Propofol - Wikipedia

    en.wikipedia.org/wiki/Propofol

    To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).

  3. List of Schedule IV controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_IV...

    The drug or other substance has a currently accepted medical use in treatment in the United States. Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III. The complete list of Schedule IV substances is as follows.

  4. Phenazepam - Wikipedia

    en.wikipedia.org/wiki/Phenazepam

    Phenazepam is a drug of the benzodiazepine class. Benzodiazepine drugs contain a benzene ring fused to a diazepine ring, which is a seven membered ring with the two nitrogen constituents located at R1 and R4. The benzyl ring of phenazepam is substituted at R7 with a bromine group.

  5. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Benzodiazepines have been shown to upregulate microglial spine engulfment and prompt overzealous eradication of synaptic connections. [186] This mechanism may help explain the increased risk of dementia associated with long-term benzodiazepine treatment. [187] The benzodiazepine class of drugs also interact with peripheral benzodiazepine receptors.

  6. GABAA receptor positive allosteric modulator - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor_positive...

    He thought the compound had a heptoxdiazine structure (Figure 7) but it was later determined to be a quinazoline-3-oxide. Possible drug candidates were then synthesized from that compound and screened for activity. One of these compounds was active, chlordiazepoxide. It was marketed in 1960 and became the first benzodiazepine drug. [30]

  7. Drug rehabilitation - Wikipedia

    en.wikipedia.org/wiki/Drug_rehabilitation

    Drug rehabilitation is the process of medical or psychotherapeutic treatment for dependency on psychoactive substances such as alcohol, prescription drugs, and street drugs such as cannabis, cocaine, heroin, and amphetamines.

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