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Ichthyosis (also named fish scale disease) [1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive, autosomal or X-linked). [3]
Many people with severe ichthyosis have problems sweating due to the buildup of scales on the skin. This may lead to problems such as "prickly itch", which results from the afflicted skin being unable to sweat due to the buildup of scales, or problems associated with overheating. The majority of people with vulgaris can sweat at least a little.
In zoology, a scale (Ancient Greek: λεπίς, romanized: lepís; Latin: squāma) is a small rigid plate that grows out of an animal's skin to provide protection. In lepidopterans ( butterflies and moths ), scales are plates on the surface of the insect wing , and provide coloration.
After as little as two weeks of daily oral isotretinoin, fissures in the skin can heal, and plate-like scales can nearly resolve. Improvement in the eclabium and ectropion can also be seen in weeks. Children who survive the neonatal period usually develop a less severe phenotype, resembling a severe congenital ichthyosiform erythroderma .
A fish scale is a small rigid plate that grows out of the skin of a fish. The skin of most jawed fishes is covered with these protective scales , which can also provide effective camouflage through the use of reflection and colouration , as well as possible hydrodynamic advantages.
Kerecis is an Icelandic company that uses fish skins to treat wounds. [3] [4] The decellularized skin of the Atlantic cod is used as a graft, which increases the elasticity, tensile strength, and compressibility of the wound. [5] Kerecis has subsidiaries in Switzerland and the United States. [6] It is based in Ísafjörður, Iceland. [7] [8]
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In around 10% of cases the baby sheds this layer of skin and has normal skin for the rest of its life. [2] [5] This is known as self-healing collodion baby. The remaining 15% of cases are caused by a variety of diseases involving keratinization disorders. [5] Known causes of collodion baby include ichthyosis vulgaris and trichothiodystrophy. [3]