Ad
related to: jardiance interaction with spironolactone 5- Savings Card
Are You Eligible For Savings?
See If You Qualify.
- What Jardiance Can Do
Learn More Information.
How JARDIANCE Can Help.
- About Jardiance
Learn More About What Jardiance
Is And What It Can Do.
- JARDIANCE Dosing
Find Dosing Info & Guidance
For Getting Started.
- Sign Up For Savings
Check Your Savings Eligibility.
Pay As Little As $10/Month.
- What To Expect
Learn How To Take Jardiance
And The Possible Side Effects.
- Savings Card
Search results
Results From The WOW.Com Content Network
Help; Learn to edit; Community portal; Recent changes; Upload file; Special pages
Empagliflozin, sold under the brand name Jardiance (/ ˈ dʒ ɑːr d i ə n s / JAR-dee-əns), among others, is an antidiabetic medication used to improve glucose control in people with type 2 diabetes. [12] [2] [14] It is taken by mouth. [2]
Side effects of spironolactone which may be indicative of hyperkalemia and if persistent could justify serum potassium testing include nausea, fatigue, and particularly muscle weakness. [64] Notably, non-use of routine potassium monitoring with spironolactone in young women would reduce costs associated with its use. [64]
For premium support please call: 800-290-4726 more ways to reach us
This article showcases a curated list of standout studies over the last week on topics such as cholesterol, GLP-1 drugs for weight loss, and supplements for heart health.
Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]
[12] [13] Due to its activity as an androgen receptor antagonist and progesterone receptor agonist, spironolactone causes adverse effects, including gynecomastia or decreased libido in males and menstrual abnormalities in females. [14] Spironolactone also causes hyperkalemia [15] and renal insufficiency. [16]
Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]
Ad
related to: jardiance interaction with spironolactone 5