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In the United States, the first restrictions on sale of cannabis came in 1906 (in the District of Columbia). [218] Canada criminalized cannabis in The Opium and Narcotic Drug Act, 1923, [219] before any reports of the use of the drug in Canada, but eventually legalized its consumption for recreational and medicinal purposes in 2018. [16]
As of 10 October 2019 194 authorized licensed medical marijuana producers have been approved by Health Canada. Including: [1] Aurora Cannabis; Aphria; CanniMed; Canopy Growth Corporation; Organigram; Tantalus Labs; The Green Organic Dutchman; Tilray; VIVO Cannabis; Zenabis
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [22] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9-THC), the compound commonly known as THC, with which it co-occurs in hemp; natural quantities of ∆ 8-THC found in hemp are low.
Cannabis also has a long history of being used for medicinal purposes, and as a recreational drug known by several slang terms, such as marijuana, pot or weed. Various cannabis strains have been bred, often selectively to produce high or low levels of tetrahydrocannabinol (THC), a cannabinoid and the plant's principal psychoactive constituent.
Δ 9-tetrahydrocannabinol (THC) Cannabis sativa, scientific drawing from c. 1900 Although the main psychoactive constituent of Cannabis is tetrahydrocannabinol (THC), the plant is known to contain more than 500 compounds, among them at least 113 cannabinoids ; however, most of these "minor" cannabinoids are only produced in trace amounts. [ 10 ]
Bedrocan is a medicinal cannabis variety cultivated from a Dutch medical marijuana Cannabis sativa L. strain, having a standardized content of THC (22%) and CBD (1%). It is currently cultivated by Bedrocan Nederland, Bedrocan Canada and Bedrocan Danmark.
Cannabis in Saskatchewan became legal when the national Cannabis Act went into force on 17 October 2018.. Cannabis in Canada has been legal for medicinal purposes since 2001 under conditions outlined in the Marihuana for Medical Purposes Regulations, later superseded by the Access to Cannabis for Medical Purposes Regulations, [1] issued by Health Canada and seed, grain, and fibre production ...