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Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [ 2 ] [ 3 ] The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. [ 4 ]
PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck ( IC 50 =4 nM ), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM).
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Second-wave positive psychology (PP 2.0) is a therapeutic approach in psychology that attempts to bring out the best in individuals and society by incorporating the dark side of human existence through the dialectical principles of yin and yang.
Walther PP .32 made in Germany in 1968. The original PP was released in 1929. [1] It was designed for police use and was used by police forces in Europe in the 1930s and later. [1]
The metal body of the PSO-1 is made from a magnesium alloy. The PSO-1 features a battery-powered red illuminated reticle with light provided by a simple diode bulb. It features professionally ground, fully multi-coated optical elements, a baked enamel finish for scratch protection, and an attached, quick-deployable, extendable sunshade.
The full extent of the payment became clear only twelve years later, in 1993, during the mani pulite (Italian for "clean hands") investigations into political corruption. The money was allegedly a kickback on a loan which the Socialist leaders had organised to help bail out the ailing Banco Ambrosiano .
PPS-43s were seldom captured by the Germans, unlike the PPS-42, as the Red Army was no longer on the defensive in 1943. Finland M/44 submachine gun . The M/44 was a modified copy with minor differences to the original PPS-43, including a straight rather than curved box magazine.