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PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck ( IC 50 =4 nM ), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM).
Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [ 2 ] [ 3 ] The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. [ 4 ]
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System Mechanic is an easy solution for optimal PC performance and simple computing. Once downloaded, it helps speed up slow computers by removing unnecessary software and files and fixes problems ...
Hare Remover is a Merrie Melodies cartoon starring Bugs Bunny and Elmer Fudd, released in 1946. [3] The film was the second Bugs Bunny cartoon to be directed by Frank Tashlin, the first being The Unruly Hare (1945). [4] It was also the last short Tashlin directed before leaving Warner Bros. in late-1944 to direct live-action films.