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Gadoteridol is a gadolinium-based MRI contrast agent, used particularly in the imaging of the central nervous system. It is sold under the brand name ProHance . [ 3 ] Gadoteridol was first approved for use in the United States in 1992.
Each patient received a single dose of gadobutrol (0.1 mmol/kg body weight) via intravenous injection, followed by a single dose of gadoteridol (ProHance) at the approved dose (0.1 mmol/kg body weight) via intravenous injection, or vice versa. The study evaluated safety and efficacy of gadobutrol.
MRI contrast agents may be administered by injection into the blood stream or orally, depending on the subject of interest. Oral administration is well suited to gastrointestinal tract scans, while intravascular administration proves more useful for most other scans. MRI contrast agents can be classified [2] by their: Chemical composition
Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle-structured gadolinium-based MRI contrast agent (GBCA).It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine).
A bottle of Omniscan contrast agent. Gadodiamide is a contrast medium used for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration.
Gadobenic acid (INN, brand name Multihance) is a complex of gadolinium with the ligand BOPTA. In the form of the methylglucamine salt meglumine gadobenate or gadobenate dimeglumine (), it is used as a gadolinium-based MRI contrast medium.
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Gadopiclenol was approved for medical use in the United States in September 2022 by the Food and Drug Administration. [2] [12]In October 2023, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Elucirem, intended for contrast-enhanced ...