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This treatment option is an alternative to remove testicular cancer masses which are <20 mm, have a high probability of being benign, and with negative serum tumor markers. Its benefits include preserving fertility and normal hormone function. [7] About half of testicular cancer germ cell tumors are seminomas. Individuals with seminomas are 80 ...
Testicular cancer is highly treatable and usually curable. [5] Treatment options may include surgery, radiation therapy, chemotherapy, or stem cell transplantation. [2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%. [4] Globally testicular cancer affected about 686,000 people in 2015. [6]
Testicular cancer metastasizes in a predictable pattern, and lymph nodes in the retroperitoneum are typically the first place it lands. [1] [2] By examining the removed lymphatic tissue, a pathologist can determine whether the disease has spread. If no malignant tissue is found, the cancer can be labeled Stage I, limited to the testicle. [3]
Cisplatin is particularly effective against testicular cancer; the cure rate was improved from 10% to 85%. [10] Similarly, the addition of cisplatin to adjuvant chemotherapy led to a marked increase in disease-free survival rates for patients with medulloblastoma - again, up to around 85%.
Second-line treatment is the same as for nonseminomas. [12] Stage 3 seminoma is characterized by the presence of metastasis outside the retroperitoneum—the lungs in "good risk" cases or elsewhere in "intermediate risk" cases. This is treated with combination chemotherapy. Second-line treatment follows nonseminoma protocols. [12]
Vinblastine—used to treat leukaemia, Hodgkin's lymphoma, non-small cell lung cancer, breast cancer and testicular cancer. It is also a component in a large number of chemotherapy regimens. Vinblastine and vincristine were isolated from the Madagascar periwinkle Catharanthus roseus, traditionally used to treat diabetes. In fact it has been ...
The inguinal orchiectomy is a necessary procedure if testicular cancer is suspected. While it is possible to remove a testicle through an incision in the scrotum, this is not done when cancer is suspected because it disrupts the natural lymphatic drainage patterns. Testicular cancer usually spreads into the lymph nodes inside the abdomen in a ...
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]