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The rabies vaccine is a vaccine used to prevent rabies. [11] There are several rabies vaccines available that are both safe and effective. [ 11 ] Vaccinations must be administered prior to rabies virus exposure or within the latent period after exposure to prevent the disease. [ 12 ]
The rabies vaccine is 100% effective if given before symptoms of rabies appear. [ 34 ] [ 36 ] [ 84 ] Every year, more than 15 million people get vaccinated after potential exposure. While this works well, the cost is significant. [ 85 ]
The vaccine for rabies can be administered prior or post to being infected, as a result of the long incubation period of the disease. [20] The proactive approach of vaccinating stray dogs, which helps to prevent the disease at its source, has been seen to be the most cost-effective prevention of rabies.
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Rabies has a long history of association with dogs. The first written record of rabies is in the Codex of Eshnunna (c. 1930 BC), which dictates that the owner of a dog showing symptoms of rabies should take preventive measure against bites. If a person was bitten by a rabid dog and later died, the owner was fined heavily.
Dog vaccination against rabies. Vaccination of dogs is the practice of animal vaccination applied to dogs. Programs in this field have contributed both to the health of dogs and to the public health. In countries where routine rabies vaccination of dogs is practiced, for example, rabies in humans is reduced to a very rare event.
The treatment consists of a series of injections of rabies vaccine and immunoglobulin. [7] Rabies vaccine is given to both humans and animals who have been potentially exposed to rabies. [8] As of 2018, the average estimated cost of rabies post-exposure prophylaxis was US$ 108 (along with travel costs and loss of income). [9]
Interestingly, the rabies virus vaccine that was created using the SAD-B19 complex, which includes the L-P protein, was utilized in the creation of a vaccine for SARS-CoV-2. The S1 protein from SARS-CoV-2 was inserted into the rabies virus vaccine vector to create a new vaccine that was shown to be effective in protecting against COVID-19.